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Yes — the core Wolfram Language uses only standard QWERTY keyboard characters.
You do not need any custom keyboard, special hardware, or non-standard symbols to write almost all Wolfram Language code. Everything essential can be typed with ordinary letters (A–Z, a–z), numbers (0–9), and the common symbols found on a normal keyboard:
There are optional special characters (Greek letters, mathematical symbols, etc.) that you can enter with Esc sequences (for example, type Esc p Esc to get π), but they are never required for normal programming. You can always write everything in plain ASCII.
Summary
You can write essentially all Wolfram Language code using only the normal letters, numbers, and symbols on a standard QWERTY keyboard.
Square brackets [ ] are used for functions (this is the biggest visual difference from most other languages).
Curly braces { } are used for lists.
The underscore _ is extremely important for patterns and function arguments.
:= is the usual way to define functions.
Special mathematical characters are optional conveniences, not requirements.

An Introduction to the Wolfram Language for Complete Beginners
You have never studied the Wolfram Language before. That is perfectly fine. This short guide (roughly 4900 characters) introduces what it is, how it works, and shows simple examples so you can start understanding it immediately.

What Is the Wolfram Language?

The Wolfram Language is a high-level computational language created by Stephen Wolfram and the team at Wolfram Research. It powers Mathematica, Wolfram|Alpha, and the Wolfram Cloud. Unlike traditional programming languages such as Python, Java, or C++, which focus mainly on telling a computer step-by-step instructions, the Wolfram Language is knowledge-based and symbolic.
This means two important things:

1. Vast amounts of knowledge about mathematics, science, geography, data, images, and algorithms are built directly into the language.
2. Almost everything is treated as a symbolic expression that can be manipulated, transformed, or evaluated.
   You do not need to load external libraries for most common tasks. Functions for solving equations, plotting graphs, analyzing images, querying real-world data, or generating interactive interfaces already exist and work consistently together.

How It Works — Core Ideas

• Everything is an expression. Numbers, lists, functions, graphics, and even programs themselves are symbolic expressions.
• Functions use square brackets. Built-in functions start with a capital letter: Sin[x], Plot[...], Factor[...].
• Evaluation is automatic. You type an expression and press Shift+Enter (in a notebook). The system evaluates it and returns the result.
• Symbolic and numerical computation live together. You can leave variables undefined and still manipulate formulas, or ask for numerical answers when needed.
• High automation. The language tries to do as much as possible for you—choosing algorithms, handling units, formatting output, etc.
  You usually work in a notebook interface (desktop or cloud). Input cells are labeled In[n]:= and output appears below as Out[n]=.

Simple Examples

1. Basic arithmetic (just like a calculator)

2 + 2

Result: 4

9.7^200

Gives a very large number instantly.
2. Symbolic algebra

Factor[x^25 - 1]

The system factors the polynomial automatically into linear and higher-degree factors.
3. Using functions

Sin[Pi/2]

Result: 1

Plot[Sin[x], {x, 0, 2 Pi}]

Draws a sine wave graph from 0 to 2π.
4. Lists and operations

{1, 2, 3, 4, 5}^2

Squares every element: {1, 4, 9, 16, 25}

Range[10]

Creates the list {1, 2, 3, 4, 5, 6, 7, 8, 9, 10}.
5. Real-world knowledge

CountryData["Australia", "Population"]

Returns the current estimated population of Australia (the number is pulled from the built-in knowledgebase).

WeatherData["Sydney", "Temperature"]

Gives recent temperature data for Sydney.
6. Defining your own functions

f[x_] := x^2 + 3 x + 1
f[5]

Result: 41
The underscore _ means “any expression.” The := is a delayed assignment (the right-hand side is evaluated only when the function is called).
7. Pattern matching and rules (a powerful feature unique to symbolic languages)

{a, b, c, d} /. b -> 10

Replaces b with 10, giving {a, 10, c, d}.

Why It Feels Different

Most languages force you to manage low-level details (loops, memory, libraries). Wolfram Language lets you stay closer to the idea you want to compute. You describe what you want rather than how to do every tiny step. The system contains thousands of carefully designed functions that fit together coherently.
Because it is symbolic, the same language can handle pure mathematics, data science, machine learning, image processing, geographic mapping, and interactive web apps with a consistent syntax.

Getting Started Advice

• Use the free Wolfram Cloud or the free Wolfram Engine for Developers to try code.
• The classic free book An Elementary Introduction to the Wolfram Language by Stephen Wolfram is excellent for absolute beginners.
• Start by typing simple expressions and pressing Shift+Enter. Experiment freely—the language is designed for interactive exploration.
  You now know the basic idea: the Wolfram Language is a symbolic, knowledge-rich computational language that lets you express ideas at a high level and have the computer do the heavy lifting. The examples above are the natural starting point for anyone who has never studied it before. From here you can gradually explore lists, graphics, pure functions, patterns, and the enormous built-in knowledgebase.