A man may as well wonder that he should be cold in winter, sick at sea, or have his bones clatter together in a wagon, as at the encounter of ill accidents and crosses in the passage of human life; and it is in vain to run away from fortune, as if there were any hiding-place wherein she could not find us; or to expect any quiet from her; for she makes life a perpetual state of war, without so much as any respite or truce. This we may conclude upon, that her empire is but imaginary, and that whosoever serves her, makes himself a voluntary slave; for “the things that are often contemned by the inconsiderate, and always by the wise, are in themselves neither good nor evil:” as pleasure and pains; prosperity and adversity; which can only operate upon our outward condition, without any proper and necessary effect upon the mind.